Prostatitis enlargement with calcification what does it mean 🩺 Men may feel puzzled by this medical term. Prostate enlargement refers to the increased size of the prostate gland, a common condition among middle-aged and elderly men that can affect urethral function, leading to difficulties in urination. Calcification sites indicate calcium salt deposits in the prostate tissue, usually due to post-inflammatory sequelae or aging. This situation generally does not require special treatment but needs regular check-ups to monitor its changes. If accompanied by discomfort symptoms, it is recommended to seek medical attention and consult a professional doctor in time.