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Sci Rep:河北医科大学附属唐山工人医院王希柱揭示心血管健康与抑郁的关系

摘要 : 本周发表在《Scientific Reports》上的一则研究显示中国汉族人中拥有理想心血管健康指标的人可能不太容易抑郁。作者认为,保持不吸烟,经常做运动和保持健康的饮食可能是有价值的预防抑郁的方法,尤其是在男性和年轻人当中。

 本周发表在《Scientific Reports》上的一则研究显示中国汉族人中拥有理想心血管健康指标的人可能不太容易抑郁。作者认为,保持不吸烟,经常做运动和保持健康的饮食可能是有价值的预防抑郁的方法,尤其是在男性和年轻人当中。

过去在白人群体中已经发现了理想的心血管健康指标可以防止抑郁的现象,但没有中国人抑郁与心血管健康关系的研究。河北医科大学附属唐山工人医院的王嵬,宋巧凤和王希柱与他们的研究团队,采用了美国心脏协会建议的7个心血管健康指标和流行病学调查用抑郁自评量表(CES-D)收集了6851位超过20岁唐山居民的吸烟情况,身高体重指数,饮食摄入,体力活动,血压,总胆固醇和空腹血糖,并且评估了他们的抑郁状况。研究分析显示心血管健康指标最好的25%人群比最不好的25%人群抑郁的可能性要少42%。这种负相关性在男性参与者和小于40岁的参与者上更明显。

研究者指出他们的研究有几个局限。首先饮食摄入状况是通过问卷收集的,其次CES-D是流行病学中常使用抑郁指标,但不是临床上诊断抑郁症的工具。另外抗抑郁药物和治疗方面的信息没有被充分收集,同时这项研究中的参与者的收入和教育程度都比中国平均水平要高。

原文链接:

Association between Ideal Cardiovascular Health Metrics and Depression in Chinese Population: A Cross-sectional Study

原文摘要:

The study aimed to examine the association between ideal cardiovascular health (CVH) metrics and depression. We conducted a population-based, cross-sectional study of 6,851 participants aged 20 years or older (3,525 men and 3,326 women) living in Tangshan City, China. Information on the seven CVH metrics (including smoking, body mass index, dietary intake, physical activity, blood pressure, total cholesterol and fasting blood glucose) was collected via questionnaires, physical examination and laboratory test. Depression status was assessed using the Epidemiologic Studies Depression Scale (CES-D) and a score of 16 or above was considered depression. The relationship between CVH metrics and depression was analyzed using logistic regression. Of the 6,851 participants, 525 (7.7%) were in depression status. After adjustment for potential confounders, men in the highest quartile of ideal CVH metric summary score had a reduced likelihood of having depression compared to those in the lowest quartile (adjusted odds ratio (AOR): 0.46, 95% confidence interval (CI): 0.28–0.75, p = 0.002). A similar trend was found among women, even though the association was not significant (AOR = 0.74, 95%CI: 0.46–1.18, p = 0.211). This study suggested that better CVH status is associated with a lower risk of depression especially in Chinese male and young population.

来源: Scientific Reports 浏览次数:0

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